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Branched-chain amino acids, leucine, isoleucine, and valine, when present in adequate concentrations, are supposed to maintain plasma glutamine concentration and cytokine (interleukin-1) production, while attenuating lymphocyte proliferation. This corresponds to maintaining the integrity of the immune system. Cytokines regulate immune and inflammatory responses and glutamine maintains skeletal muscle protein when the body's need for glutamine exceeds its natural production.
Prolonged, exhaustive exercise may cause the activity of the immune response cells to be suppressed. During such periods of metabolic stress, increasing the amount of glutamine made available would increase protein synthesis, maintain glutamine production, thereby maintaining activity of the immune response cells. If glutamine is not available, muscle catabolism (degradation, breakdown) proceeds and reductions in plasma glutamine concentration are likely, leaving the body's immune system more susceptible to invasion.
BCAAs also compete with tryptophan for transport across the blood-brain barrier. If tryptophan wins, it is converted to 5-hydroxytryptomine, leading to an increase in serotoninergic neurotransmitter activity. It is well known that serotonin-like activity causes central fatigue (the "Central Fatigue Theory"). Theory has it that if BCAAs are present in concentrations high enough to win the BCAA-tryptophan battle, BCAAs could reduce the exercise-induced tryptophan uptake by the brain, thus delaying fatigue. This would allow the athlete to continue to perform.
Features online enrollment, online exam and instant grading as well as automatic certificate generation upon completion of course.
The customer service is outstanding and the re-certification process straight-forward. I highly recommend ISSA to anyone looking to get Certified in the Fitness industry.
What I loved most was the final exam not just a multiple choice exam but an exam that made me think, challenged me, but also had me prove myself from a practical stand point!
The International Sports Sciences Association certified personal trainer program has been one of the best experiences of my life
Not only was the program extremely informative, but the final exam was challenging and really put what I had learned to test.
I feel I can give my best to my clients and continue to further my education so I can give them the most up to date and relevant information.
They provide you with the academic knowledge and the real world skills you need to be a success.
Now I am a certified personal trainer. This will be my first step into the fitness world, and now, my knowledge is much greater.
They have been tremendously supportive over the years and helped me to build a very profitable personal training practice!
After completing my CPT successfully, I can say only one thing that ISSA is really good in providing you the knowledge which is required in the fitness industry. It makes you fitness industry ready in every aspect.
I simply have not ever enjoyed a certification as much as I did this one. This is by far my favorite and I thought the entire program was very well worded and engaging.
The ISSA certified personal trainer program is the best experience of my life.
ISSA has remained to be among the leaders of the fitness industry and is still an organization that is nationally recognized and has a good reputation.
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